SCHEMBL8978615

SCHEMBL8978615

CCc1cc(S(=O)(=O)c2cc(CC)c(Br)cc2CC)c(CC)cc1Br

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11807767 0.81 GABRA1 (0.46) LMNATSHRGABRA1GABRB2SMN1; SMN2
SCHEMBL10799329 0.76 GABRA1 (0.42) LMNAGABRA1GABRB2SMN1; SMN2
SCHEMBL9332580 0.74 ALOX15 (0.41) LMNAKDM4ETP53POLB
SCHEMBL9018772 0.74 GABRA1 (0.38) LMNATSHRGABRA1GABRB2
SCHEMBL21884099 0.73 GABRA1 (0.43) LMNATSHRGABRA1GABRB2SMN1; SMN2
SCHEMBL273226 0.68 ALDH1A1 (0.38) GABRA1GABRB2POLB
SCHEMBL16736693 0.68 ALOX15 (0.47) TSHRSMN1; SMN2KDM4EPOLB
SCHEMBL12115079 0.68 GRIN2D (0.50) LMNAGABRA1GABRB2
SCHEMBL5524737 0.67 CTDSP1 (0.38) LMNATSHRGABRA1GABRB2KDM4E
SCHEMBL15788771 0.67 TSHR (0.44) LMNATSHRGABRA1GABRB2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US claimed
US-5177174-A Branched aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1993-01-05 US claimed
EP-0411625-B1 Method to produce poly(arylene sulfide/sulfone) polymer PHILLIPS PETROLEUM CO (US) 1996-05-08 EP disclosed
US-5350834-A Thermal stability and purity, zinc compound PHILLIPS PETROLEUM COMPANY (US) 1994-09-27 US disclosed
US-5331069-A Method of treating poly(arylene sulfide sulfone) polymers and polymers PHILLIPS PETROLEUM COMPANY (US) 1994-07-19 US disclosed
US-5298574-A Copolymerizing in presence of n-methyl-2-pyrrolidone, sodium carbonate and sodium hydrogen sulfide PHILLIPS PETROLEUM COMPANY (US) 1994-03-29 US disclosed
US-5298573-A Poly(arylene sulfide sulfone)/poly(arylene sulfide ketone) block copolymers and preparation thereof PHILLIPS PETROLEUM COMPANY (US) 1994-03-29 US disclosed
US-5286817-A Poly(arylene sulfide)/poly(arylene sulfide sulfone) block copolymers and preparation thereof PHILLIPS PETROLEUM COMPANY (US) 1994-02-15 US disclosed
US-5268449-A Containing arylene sulfide and arylene sulfonate segments PHILLIPS PETROLEUM COMPANY (US) 1993-12-07 US disclosed
US-5266674-A Copolymers PHILLIPS PETROLEUM COMPANY (US) 1993-11-30 US disclosed
US-5235034-A Increased melt stability and decreased impurities PHILLIPS PETROLEUM COMPANY (US) 1993-08-10 US disclosed
US-4774276-A ZINC IONS TO IMPROVE MELT STABILITY OF POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1988-09-27 US disclosed
EP-0280325-A2 Melt stabilization of poly (arylene sulfide sulfone) S PHILLIPS PETROLEUM COMPANY (US) 1988-08-31 EP disclosed
EP-0033906-B1 PROCESS FOR THE PRODUCTION OF AROMATIC SULFIDE/SULFONE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1985-05-15 EP disclosed
US-4301274-A BY REACTING A DIHALOAROMATIC SULFONE, AND AN ALKALI METAL SULFIDE; ENDCAPPING PHILLIPS PETROLEUM COMPANY (US) 1981-11-17 US disclosed
US-4127713-A FORM A DIHALOAROMATIC SULFONE, ALKALI METAL SULFIDE, AMIDE, SODIUM CARBOXYLATE AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-11-28 US disclosed
US-4125525-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed
US-4102875-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-07-25 US disclosed
US-4070349-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-01-24 US disclosed
US-4016145-A SULFONE POLYMERSREACTING A DIHALO AROMATIC SULFONE, AN ALKALI METAL SULFIDE, AN ALKALI METAL CARBOXYLATE, AND AN AMIDE PHILLIPS PETROLEUM COMPANY (US) 1977-04-05 US disclosed