Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490523 | 0.89 | NFKB1 (0.53) | NFKB1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL7564951 | 0.87 | KDR (0.58) | KDREGFRABCG2 | |
| SCHEMBL20820089 | 0.87 | NFKB1 (0.76) | NFKB1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL8526184 | 0.81 | NFKB1 (0.69) | NFKB1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL28176787 | 0.79 | NFKB1 (0.52) | NFKB1MAPTPOLBAPPNPC1 | |
| SCHEMBL23321165 | 0.79 | NFKB1 (1.00) | NFKB1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL2874930 | 0.79 | NFKB1 (0.65) | NFKB1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL8973538 | 0.79 | NFKB1 (0.65) | NFKB1KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL2779096 | 0.79 | BRAF (0.52) | MAPTKDRPOLBEGFRLMNA | |
| SCHEMBL18385064 | 0.79 | NFKB1 (0.65) | NFKB1KMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621787-A | Substituted triazine compound, method for preparing cyclic peptide and staple peptide by using same and application of substituted triazine compound | 粤港澳大湾区精准医学研究院(广州) | 2023-08-22 | — | — | CN | disclosed |
| US-5561131-A | INCREASING THE WOOL GROWTH BY ADMINISTERING AN ANTIPROTOZOA AGENT TO SHEEP | MALLINCKRODT VETERINARY, INC. (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0661976-A1 | DEFAUNATION METHOD | MALLINCKRODT VETERINARY LIMITED (AU) | 1995-07-12 | — | — | EP | disclosed |
| EP-0661976-A4 | DEFAUNATION METHOD. | MALLINCKRODT VETERINARY LTD (AU) | 1994-07-20 | — | — | EP | disclosed |
| WO-1993002680-A1 | DEFAUNATION METHOD | PITMAN-MOORE AUSTRALIA LIMITED (AU) | 1993-02-18 | — | — | WO | disclosed |