Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490523 | 0.89 | NFKB1 (0.53) | BRAFKDREGFRLMNAMAPT | |
| SCHEMBL7564951 | 0.87 | KDR (0.58) | KDREGFRADRB2ABCG2 | |
| SCHEMBL2456892 | 0.85 | ALDH1A1 (0.53) | BRAFKDREGFRLMNAMAPT | |
| SCHEMBL23412597 | 0.84 | RHOA (0.47) | BRAFKDREGFRLMNAMAPT | |
| SCHEMBL29887268 | 0.84 | RHOA (0.47) | BRAFKDREGFRLMNAMAPT | |
| SCHEMBL28918145 | 0.82 | KDR (0.46) | BRAFKDREGFRADRB2AGPAT2 | |
| SCHEMBL23130650 | 0.81 | MAPT (0.57) | EGFRLMNAMAPTNPC1RAB9A | |
| SCHEMBL24824840 | 0.80 | MAPT (0.51) | LMNAMAPTNPC1RAB9ANOD1 | |
| SCHEMBL8978637 | 0.79 | NFKB1 (0.65) | KDREGFRLMNAMAPTNPC1 | |
| SCHEMBL14869768 | 0.79 | RAB9A (0.73) | LMNAMAPTNPC1RAB9ANOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101616945-B | Polyurethane foam containing flame-retardant mixture | SUPRESTA LLC US | 2012-10-03 | — | — | CN | disclosed |
| US-20100137465-A1 | PHOSPHATE ESTER FLAME RETARDANT AND RESINS CONTAINING SAME | ICL-IP AMERICA INC. | 2010-06-03 | — | — | US | disclosed |
| US-20100137467-A1 | POLYURETHANE FOAM CONTAINING FLAME-RETARDANT MIXTURE | ICL-IP AMERICA INC. | 2010-06-03 | — | — | US | disclosed |
| US-20100063169-A1 | PHOSPHORAMIDE ESTER FLAME RETARDANT AND RESINS CONTAINING SAME | ICL-IP AMERICA INC. | 2010-03-11 | — | — | US | disclosed |
| CN-101616945-A | The polyurethane foam that contains flame-retardant mixture | SUPRESTA LLC | 2009-12-30 | — | — | CN | disclosed |
| EP-2091991-A2 | POLYURETHANE FOAM CONTAINING FLAME-RETARDANT MIXTURE | Supresta LLC (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008118154-A2 | POLYURETHANE FOAM CONTAINING FLAME-RETARDANT MIXTURE | SUPRESTA LLC (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008085924-A1 | PHOSPHATE ESTER FLAME RETARDANT AND RESINS CONTAINING SAME | SUPRESTA LLC (US) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008085926-A1 | PHOSPHORAMIDE ESTER FLAME RETARDANT AND RESINS CONTAINING SAME | SUPRESTA LLC (US) | 2008-07-17 | — | — | WO | disclosed |
| US-6617379-B2 | N,N'-piperazinebis(neopentylglycol)phosphoramidate in combination with at least one co-additive which is either melamine or a melamine derivative such as melamine cyanurate or melamine pyrophosphate | ALBEMARLE CORPORATION | 2003-09-09 | — | — | US | disclosed |
| WO-2003048247-A1 | FLAME RETARDANT POLYMER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2003-06-12 | — | — | WO | disclosed |
| US-20030109608-A1 | Flame retardant polymer compositions | ALBEMARLE CORPORATION | 2003-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137465-A1 | PHOSPHATE ESTER FLAME RETARDANT AND RESINS CONTAINING SAME | PFAS, PFKFB3, PFKFB2 | BRAF 1184/4885KDR 1291/4885EGFR 3598/4885 |
| US-20100063169-A1 | PHOSPHORAMIDE ESTER FLAME RETARDANT AND RESINS CONTAINING SAME | PFAS, RARA, PPARA | BRAF 705/4885KDR 1838/4885EGFR 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.