Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 5/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977634 | 0.85 | P2RX7 (0.37) | CYP1A2GRIA1CACNG8TRPV1LMNA | |
| SCHEMBL29937335 | 0.85 | GRIA1 (0.33) | KMT2ACYP1A2CYP2A6GRIA1CACNG8 | |
| SCHEMBL2091798 | 0.85 | TSHR (0.45) | KMT2AGRIA1CACNG8TRPV1LMNA | |
| SCHEMBL16957701 | 0.85 | GRIA1 (0.33) | KMT2ACYP1A2CYP2A6GRIA1CACNG8 | |
| SCHEMBL2091796 | 0.85 | GRIA1 (0.39) | KMT2ACYP1A2CYP2A6GRIA1CACNG8 | |
| SCHEMBL10873536 | 0.85 | GRIA1 (0.33) | KMT2ACYP1A2CYP2A6GRIA1CACNG8 | |
| SCHEMBL2095848 | 0.85 | GRIA1 (0.33) | KMT2ACYP1A2CYP2A6GRIA1CACNG8 | |
| SCHEMBL16957704 | 0.85 | KDM4E (0.44) | CYP1A2GRIA1CACNG8TRPV1LMNA | |
| SCHEMBL2095845 | 0.85 | GRIA1 (0.36) | KMT2ACYP1A2CYP2A6GRIA1CACNG8 | |
| SCHEMBL7928096 | 0.85 | TSHR (0.43) | KMT2ACYP1A2GRIA1CACNG8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| US-20220185815-A1 | PYRROLOPYRAZOLE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-06-16 | — | — | US | disclosed |
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-02-04 | — | — | US | disclosed |
| EP-2782448-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2017-08-16 | — | — | EP | disclosed |
| CN-104039149-B | Boron-containing small molecules | 安纳考尔医药公司 | 2016-11-16 | — | — | CN | disclosed |
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-01-07 | — | — | US | disclosed |
| US-9156860-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-20150025038-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2015-01-22 | — | — | US | disclosed |
| US-8853186-B2 | Boron containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2782448-A1 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| CN-104039149-A | Boron-containing small molecules | ANACOR PHARMACEUTICALS INC | 2014-09-10 | — | — | CN | disclosed |
| WO-2013078070-A1 | BORON-CONTAINING SMALL MOLECULES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| EP-0546391-B1 | Process for the preparation of fluorine containing anilines. | BAYER AG (DE) | 1996-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | KMT2A 2331/4885CYP1A2 2434/4885CYP2A6 1150/4885 |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | KMT2A 2331/4885CYP1A2 2434/4885CYP2A6 1150/4885 |
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | AFF2, AFF4, AFF1 | KMT2A 349/4885CYP1A2 133/4885CYP2A6 464/4885 |
| US-20220185815-A1 | PYRROLOPYRAZOLE DERIVATIVE | PTDSS1, PTDSS2, SMPD1 | KMT2A 3060/4885CYP1A2 2179/4885CYP2A6 3070/4885 |
| US-20150025038-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | KMT2A 2331/4885CYP1A2 2434/4885CYP2A6 1150/4885 |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | KMT2A 349/4885CYP1A2 133/4885CYP2A6 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.