Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.70 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351367 | 0.92 | OPRD1 (0.73) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL14516209 | 0.90 | OPRM1 (0.75) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL1685975 | 0.90 | OPRM1 (0.75) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL24971 | 0.90 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL14516212 | 0.90 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL29392212 | 0.90 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL15757784 | 0.90 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL16922138 | 0.90 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL15653227 | 0.90 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL14611951 | 0.90 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467078-B1 | An analyte-subtitute reagent for use in specific binding assay methods, devices and kits | ABBOTT LAB (US) | 1996-05-08 | — | — | EP | disclosed |
| US-5501985-A | DETERMINATION OF LOW MOLECULAR WEIGHT, STEROIDS, HORMONES, ANTIBIOTICS, DRUGS | ABBOTT LABORATORIES (US) | 1996-03-26 | — | — | US | disclosed |
| US-5340748-A | Analyte-substitute reagent for use in specific binding assay methods, devices and kits | ABBOTT LABORATORIES (US) | 1994-08-23 | — | — | US | disclosed |
| US-5260441-A | Fluorescence polarization process for detecting unauthorized consumption of morphine | ABBOTT LABORATORIES (US) | 1993-11-09 | — | — | US | disclosed |
| US-5258512-A | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0467078-A2 | An analyte-subtitute reagent for use in specific binding assay methods, devices and kits | ABBOTT LABORATORIES (US) | 1992-01-22 | — | — | EP | disclosed |
| US-4939264-A | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0254120-A2 | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1988-01-27 | — | — | EP | disclosed |