Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.75 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.75 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.75 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.75 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.75 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685975 | 1.00 | OPRM1 (0.75) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Hydrochloric Acid SCHEMBL6848238 | 0.99 | OPRM1 (0.74) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL2351367 | 0.91 | OPRD1 (0.73) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL28786036 | 0.91 | OPRD1 (0.69) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL8978975 | 0.90 | OPRM1 (0.70) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL15757784 | 0.89 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL24971 | 0.89 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL14516212 | 0.89 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL31058362 | 0.89 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL14611951 | 0.89 | OPRD1 (0.80) | OPRM1OPRD1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199129-B2 | Derivatives of morphine-like opioid compounds | MONASH UNIVERSITY (AU) | 2007-04-03 | — | — | US | disclosed |
| US-7199129-B2 | Derivatives of morphine-like opioid compounds | MONASH UNIVERSITY (AU) | 2007-04-03 | — | — | US | disclosed |