SCHEMBL8979236

SCHEMBL8979236

CO[Si](C)(Cl)Cl.C[Si](Cl)(Cl)Cl.Cl[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
CA4 P22748 1/20 0.33
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23898214 0.83 ESR1 (0.42) ESR1ESR2
SCHEMBL17819217 0.82 POLB (0.34) ESR1ESR2CA4POLB
Benzene SCHEMBL28553774 0.80 TSHR (0.39) ESR1ESR2CA4
SCHEMBL38744 0.80 TSHR (0.39) ESR1ESR2CA4
Methane SCHEMBL10789435 0.77 TSHR (0.37) ESR1ESR2CA4
Fluoride SCHEMBL28289678 0.77 TSHR (0.37) ESR1ESR2CA4
SCHEMBL27943171 0.77 TSHR (0.37) ESR1ESR2CA4
SCHEMBL4195240 0.76 ESR1 (0.38) ESR1ESR2CA4POLB
SCHEMBL1224337 0.73 CA4 (0.38) ESR1ESR2CA4POLB
SCHEMBL10824434 0.73 CA4 (0.38) ESR1ESR2CA4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0541395-B1 Coating agents TAKEMOTO OIL & FAT CO LTD (JP) 1996-05-08 EP disclosed
EP-0541395-A1 Coating agents Takemoto Yushi Kabushiki Kaisha (JP) 1993-05-12 EP disclosed