Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671847 | 0.73 | CYP2C19 (0.42) | ALDH1A1KMT2AKDM4ECYP2C19CYP1A2 | |
| SCHEMBL8979350 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL27483996 | 0.71 | — | — | |
| SCHEMBL2363953 | 0.71 | MEN1 (0.41) | KMT2AMEN1 | |
| SCHEMBL5505461 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL27976224 | 0.69 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL616174 | 0.69 | ALDH1A1 (0.57) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL1985443 | 0.69 | ALDH1A1 (0.57) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL27906586 | 0.69 | CYP2C19 (0.46) | ALDH1A1TSHRKMT2AKDM4ECYP2C19 | |
| SCHEMBL27498066 | 0.69 | ALDH1A1 (0.57) | ALDH1A1TSHRHTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710225-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN Biotechnik GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995032181-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN BIOTECHNIK GMBH (DE) | 1995-11-30 | — | — | WO | disclosed |