Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106656 | 0.78 | — | — | |
| SCHEMBL8979455 | 0.74 | MEN1 (0.36) | KMT2AMEN1KIF11 | |
| SCHEMBL8979343 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TSHRHTTKMT2AMEN1 | |
| SCHEMBL5505461 | 0.68 | ALDH1A1 (0.36) | ALDH1A1TSHRHTTKMT2AMEN1 | |
| SCHEMBL10410715 | 0.68 | TSHR (0.40) | ALDH1A1TSHRHTTKMT2AMEN1 | |
| SCHEMBL8979349 | 0.67 | CYP2C19 (0.35) | ALDH1A1TSHRHTTMAPTKIF11 | |
| Ethylene Glycol SCHEMBL11275979 | 0.66 | KIF11 (0.45) | ALDH1A1TSHRKIF11KDM4E | |
| SCHEMBL11430497 | 0.66 | GRIN1 (0.33) | ALDH1A1KIF11KDM4E | |
| SCHEMBL901348 | 0.66 | CA1 (0.31) | — | |
| SCHEMBL6139504 | 0.65 | TSHR (0.50) | ALDH1A1TSHRHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710225-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN Biotechnik GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995032181-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN BIOTECHNIK GMBH (DE) | 1995-11-30 | — | — | WO | disclosed |