Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979346 | 0.90 | GABRA1 (0.34) | GABRA1GABRB2ALDH1A1TSHRADRB2 | |
| SCHEMBL465453 | 0.77 | CYP2C19 (0.39) | ALDH1A1LMNACYP1A2CYP2D6KDM4E | |
| SCHEMBL8979339 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TSHRADRB2ADRB1LMNA | |
| SCHEMBL9471419 | 0.71 | GABRA1 (0.41) | GABRA1GABRB2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL9453918 | 0.69 | AGTR1 (0.39) | ALDH1A1TSHRLMNACYP1A2KDM4E | |
| Hydrogen Peroxide SCHEMBL7819301 | 0.67 | GABRA1 (0.58) | GABRA1GABRB2ALDH1A1TSHRADRB2 | |
| Hydrogen Peroxide SCHEMBL10784213 | 0.67 | GABRA1 (0.58) | GABRA1GABRB2ALDH1A1TSHRADRB2 | |
| SCHEMBL7784196 | 0.67 | ALDH1A1 (0.42) | GABRA1GABRB2ALDH1A1TSHRKDM4E | |
| 2-Allylphenol SCHEMBL5487968 | 0.66 | GABRA1 (0.46) | GABRA1GABRB2ALDH1A1TSHRADRB2 | |
| SCHEMBL9295957 | 0.66 | ALDH1A1 (0.43) | GABRA1GABRB2ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710225-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN Biotechnik GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995032181-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN BIOTECHNIK GMBH (DE) | 1995-11-30 | — | — | WO | disclosed |