SCHEMBL8979363

SCHEMBL8979363

C=CCOCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)OCCCCC

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 5/20 0.49
PLA2G10 O15496 4/20 0.49
PLA2G1B P04054 3/20 0.49
PLA2G5 P39877 3/20 0.49
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KIF11 P52732 1/20 0.34
LPAR1 Q92633 4/20 0.33
LPAR3 Q9UBY5 4/20 0.33
LPAR2 Q9HBW0 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
LTA4H P09960 1/20 0.32
TLR2 O60603 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979451 0.87 PLA2G2A (0.54) PLA2G2APLA2G10PLA2G1BPLA2G5KIF11
SCHEMBL2232632 0.87 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2231918 0.87 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL702789 0.87 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2234605 0.87 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2232437 0.87 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL1963642 0.87 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2232582 0.87 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL2233038 0.87 PLA2G2A (0.49) PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1
SCHEMBL8357825 0.87 PLA2G2A (0.59) PLA2G2APLA2G10PLA2G1BPLA2G5KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710225-A1 FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES PROGEN Biotechnik GmbH (DE) 1996-05-08 EP disclosed
WO-1995032181-A1 FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES PROGEN BIOTECHNIK GMBH (DE) 1995-11-30 WO disclosed