Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979344 | 0.80 | TTR (0.58) | LMNAHTTKDM4ESMN1; SMN2TSHR | |
| SCHEMBL10201339 | 0.78 | CA5A (0.43) | LMNAHTTKDM4ETSHRTTR | |
| SCHEMBL3130004 | 0.77 | LMNA (0.47) | LMNAHTTPARP1BCAT2KDM4E | |
| SCHEMBL30325618 | 0.75 | HSD11B1 (0.50) | LMNAHTTPARP1BCAT2KDM4E | |
| SCHEMBL4104322 | 0.75 | TTR (0.62) | LMNAHTTPARP1BCAT2CYP3A4 | |
| SCHEMBL811037 | 0.75 | LMNA (0.46) | LMNAHTTPARP1BCAT2KDM4E | |
| SCHEMBL18602709 | 0.74 | PARP1 (0.45) | LMNAHTTPARP1CYP3A4SMN1; SMN2 | |
| SCHEMBL1003805 | 0.73 | LMNA (0.49) | LMNAHTTPARP1BCAT2KDM4E | |
| SCHEMBL27851699 | 0.73 | LMNA (0.44) | LMNAHTTPARP1BCAT2KDM4E | |
| SCHEMBL27864269 | 0.73 | HTT (0.44) | LMNAHTTPARP1BCAT2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604019-B1 | N-Acetonylbenzamides and their use as fungicides | ROHM & HAAS (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0604019-A1 | N-Acetonylbenzamides and their use as fungicides | ROHM AND HAAS COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5254584-A | Controlling phytopathogens | ROHM AND HAAS COMPANY (US) | 1993-10-19 | — | — | US | disclosed |