Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.44 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1472555 | 0.88 | LMNA (0.66) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL11404787 | 0.84 | ALDH1A1 (0.68) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL8705157 | 0.84 | ALDH1A1 (0.68) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL16691726 | 0.84 | ALDH1A1 (0.59) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL15068944 | 0.84 | ALDH1A1 (0.59) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL859720 | 0.84 | ALDH1A1 (0.59) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL19816825 | 0.84 | ALDH1A1 (0.59) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL19816482 | 0.84 | ALDH1A1 (0.59) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL4624978 | 0.84 | ALDH1A1 (0.59) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 | |
| SCHEMBL8390655 | 0.84 | ALDH1A1 (0.59) | HDAC1HDAC3HDAC2NCOR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710225-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN Biotechnik GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995032181-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN BIOTECHNIK GMBH (DE) | 1995-11-30 | — | — | WO | disclosed |