SCHEMBL8979447

SCHEMBL8979447

C=CC(NCCS(=O)(=O)O)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.36
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
GRM7 Q14831 1/20 0.35
SRC P12931 1/20 0.35
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
PMP22 Q01453 2/20 0.34
GMNN O75496 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4445401 0.81 MTOR (0.52) CYP2C19MTORRAB9AGRM7CYP3A4
SCHEMBL10388847 0.79 MTOR (0.38) CYP2C19MTORRAB9AGRM7SRC
SCHEMBL10989196 0.78 RAB9A (0.41) CYP2C19MTORRAB9AGRM7CYP3A4
SCHEMBL10981498 0.78 CYP2C19 (0.41) CYP2C19MTORRAB9AGRM7CYP3A4
SCHEMBL30147199 0.76 CYP3A4 (0.56) CYP2C19CYP3A4ALOX15ALDH1A1KDM4E
SCHEMBL2638360 0.75 ATM (0.43) CYP2C19ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL28174803 0.75 HRH1 (0.41) CYP2C19MTORRAB9AGRM7CYP3A4
SCHEMBL10979420 0.74 SMN1; SMN2 (0.40) CYP2C19MTORRAB9AGRM7CYP3A4
SCHEMBL8458015 0.74 MTOR (0.41) CYP2C19MTORRAB9AGRM7CYP3A4
SCHEMBL9101144 0.74 ALDH1A1 (0.40) CYP2C19MTORRAB9AGRM7SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576393-A NARROW PARTICLE SIZE DISTRIBUTION; EMULSION POLYMERIZATION RICOH COMPANY, LTD. (JP) 1996-11-19 US disclosed
US-5541031-A SPHERICAL PARTICLES WITH PROTRUSIONS ON SURFACE AND NARROW PARTICLE SIZE DISTRIBUTION RICOH COMPANY, LTD. (JP) 1996-07-30 US disclosed
EP-0324529-B1 Resinous microparticles useful in powdery toner for electrophotography NIPPON PAINT CO LTD (JP) 1996-05-15 EP disclosed
US-4975475-A Containing polymer microparticles NIPPON PAINT CO., LTD. (JP) 1990-12-04 US disclosed
US-4968576-A POSITIVE CHARGING ABILITY, IMPROVED FLOWABILITY NIPPON PAINT CO., LTD. (JP) 1990-11-06 US disclosed
EP-0324529-A2 Resinous microparticles useful in powdery toner for electrophotography Nippon Paint Co., Ltd. (JP) 1989-07-19 EP disclosed
US-4543216-A REACTING A VINYL BENZYL HALIDE WITH AN AMINO ACID OR AMINO SULFONIC ACID NIPPON PAINT CO., LTD. (JP) 1985-09-24 US disclosed
US-4468493-A High solid coating composition containing novel microparticles of crosslinked copolymer containing amphoionic groups NIPPON PAINT CO., LTD. (JP) 1984-08-28 US disclosed
US-4452746-A TO MODIFY PROPERTIES OF HIGH MOLECULAR WEIGHT COMPOUNDS NIPPON PAINT CO., LTD. (JP) 1984-06-05 US disclosed
US-4403065-A CARBOXY OR SULFONATE AMINE AND OTHER MONOMER NIPPON PAINT CO., LTD. (JP) 1983-09-06 US disclosed
US-4309327-A COATINGS, PIGMENT PASTES NIPPON PAINT CO., LTD. (JP) 1982-01-05 US disclosed