Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555696 | 0.77 | CYP1A2 (0.34) | CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL8979613 | 0.74 | ATAD2 (0.40) | CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL8979523 | 0.73 | CYP1A2 (0.34) | CYP1A2CYP11B1CYP11B2DDB1CRBN | |
| SCHEMBL8557200 | 0.71 | CYP1A2 (0.33) | CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL8979516 | 0.67 | ALOX5 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL8979547 | 0.66 | ALOX5 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL9386145 | 0.64 | OPRM1 (0.37) | DDB1CRBN | |
| SCHEMBL8979512 | 0.62 | ALOX5 (0.41) | CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL8554600 | 0.61 | KCNH2 (0.40) | — | |
| SCHEMBL428384 | 0.59 | CYP11B1 (0.51) | CYP1A2CYP11B1CYP11B2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512594-A | ADMINISTERING TO TREAT A MEDICAL CONDITION MEDIATED BY ONE OR MORE LEUKOTRIENES | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |