Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979512 | 0.83 | ALOX5 (0.41) | TRIM24TRPV1CYP17A1CYP1A2CYP19A1 | |
| SCHEMBL8979554 | 0.77 | TRIM24 (0.38) | TRIM24TRPV1GABRG2GABRB3GABRA5 | |
| SCHEMBL8979495 | 0.75 | TRIM24 (0.35) | TRIM24TRPV1CYP11B1CYP11B2 | |
| SCHEMBL8979492 | 0.75 | ATAD2 (0.39) | LMNACYP1A2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL2107553 | 0.73 | TRIM24 (0.36) | TRIM24LMNAPKMCYP17A1CYP1A2 | |
| SCHEMBL9285980 | 0.72 | TRIM24 (0.37) | TRIM24LMNAPKMCYP17A1CYP1A2 | |
| SCHEMBL9286206 | 0.72 | TRIM24 (0.37) | TRIM24LMNAPKMCYP17A1CYP1A2 | |
| SCHEMBL9285981 | 0.72 | TRIM24 (0.37) | TRIM24LMNAPKMCYP17A1CYP1A2 | |
| SCHEMBL9285989 | 0.72 | TRIM24 (0.37) | TRIM24LMNAPKMCYP17A1CYP1A2 | |
| SCHEMBL8979526 | 0.72 | CYP11B1 (0.32) | TRPV1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512594-A | ADMINISTERING TO TREAT A MEDICAL CONDITION MEDIATED BY ONE OR MORE LEUKOTRIENES | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |