Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285981 | 1.00 | TRIM24 (0.37) | TRIM24ALDH1A1GAABRD4CREBBP | |
| SCHEMBL9285989 | 1.00 | TRIM24 (0.37) | TRIM24ALDH1A1GAABRD4CREBBP | |
| SCHEMBL9285980 | 1.00 | TRIM24 (0.37) | TRIM24ALDH1A1GAABRD4CREBBP | |
| SCHEMBL2107553 | 0.88 | TRIM24 (0.36) | TRIM24ALDH1A1GAABRD4CREBBP | |
| SCHEMBL9230759 | 0.86 | ALOX5 (0.41) | TRIM24ALDH1A1GAABRD4CREBBP | |
| SCHEMBL9274972 | 0.83 | ALOX5 (0.43) | TRIM24BRD4CREBBPPDE3BPDE3A | |
| SCHEMBL2108075 | 0.79 | TRIM24 (0.36) | TRIM24ALDH1A1GAABRD4CREBBP | |
| SCHEMBL9098432 | 0.77 | ALOX5 (0.42) | TRIM24ALDH1A1GAABRD4CREBBP | |
| SCHEMBL8556514 | 0.77 | ATAD2 (0.39) | ALDH1A1GAACYP11B2CYP11B1CYP1A2 | |
| SCHEMBL2108940 | 0.76 | TRIM24 (0.36) | TRIM24ALDH1A1GAABRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030668-A1 | CYCLIC ETHER DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | ZENECA LIMITED (GB) | 1995-11-16 | — | — | WO | claimed |