⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274599 | 0.83 | AGTR1 (0.36) | — | |
| SCHEMBL8979790 | 0.83 | — | — | |
| Milfasartan SCHEMBL489256 | 0.80 | — | — | |
| SCHEMBL7985567 | 0.79 | — | — | |
| SCHEMBL8979803 | 0.77 | — | — | |
| SCHEMBL8979896 | 0.75 | — | — | |
| SCHEMBL8979854 | 0.74 | ACHE (0.30) | — | |
| SCHEMBL9270308 | 0.74 | AGTR1 (0.39) | — | |
| SCHEMBL8979816 | 0.73 | AGTR1 (0.43) | — | |
| SCHEMBL8018483 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | disclosed |