⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979818 | 0.92 | — | — | |
| SCHEMBL8979900 | 0.87 | PPARG (0.42) | — | |
| SCHEMBL9539733 | 0.85 | — | — | |
| SCHEMBL8979816 | 0.83 | AGTR1 (0.43) | — | |
| SCHEMBL8979824 | 0.81 | AGTR1 (0.38) | — | |
| SCHEMBL8979790 | 0.80 | — | — | |
| SCHEMBL8028170 | 0.79 | — | — | |
| SCHEMBL9538569 | 0.78 | AGTR1 (0.51) | — | |
| SCHEMBL8979822 | 0.77 | — | — | |
| SCHEMBL8979802 | 0.77 | ACHE (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | claimed |