Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673612 | 0.90 | AGTR1 (0.49) | BRS3AGTR1AGTR2 | |
| SCHEMBL9198419 | 0.89 | BRS3 (0.53) | BRS3AGTR1AGTR2 | |
| SCHEMBL9134883 | 0.88 | BRS3 (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL9138510 | 0.88 | BRS3 (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL8802322 | 0.87 | ACHE (0.49) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979808 | 0.86 | BRS3 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979863 | 0.84 | AGTR2 (0.55) | BRS3AGTR1AGTR2 | |
| SCHEMBL9241895 | 0.84 | BRS3 (0.58) | BRS3AGTR1AGTR2 | |
| SCHEMBL8979815 | 0.83 | BRS3 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL8801326 | 0.83 | ACHE (0.45) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | disclosed |