Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980424 | 0.86 | KMT2A (0.44) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL7125937 | 0.84 | MEN1 (0.36) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL10640704 | 0.81 | PPARG (0.46) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL9533035 | 0.80 | ESR1 (0.40) | MEN1MAPTKMT2ATDP1AKT1 | |
| SCHEMBL10639162 | 0.80 | PPARG (0.41) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL9632908 | 0.80 | DDB1 (0.34) | MEN1MAPTKMT2ATDP1PTPN1 | |
| SCHEMBL8459669 | 0.80 | MEN1 (0.53) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL10977280 | 0.80 | AKT1 (0.37) | MEN1MAPTKMT2ATDP1AKT1 | |
| SCHEMBL9632649 | 0.78 | PPARG (0.31) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL10638804 | 0.78 | MEN1 (0.44) | MEN1MAPTKMT2ATDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556830-B1 | Method for the preparation of 6-hydroxy-2,5,7,8-tetraalkyl-2-(4-aminophenoxymethyl)chromans | LONZA AG (CH) | 1996-04-24 | — | — | EP | disclosed |
| EP-0556830-A1 | Method for the preparation of 6-hydroxy-2,5,7,8-tetraalkyl-2-(4-aminophenoxymethyl)chromans | LONZA AG (CH) | 1993-08-25 | — | — | EP | disclosed |