Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191312 | 0.86 | HPD (0.42) | CYP2C19FLT1FLT4KDRLMNA | |
| SCHEMBL8980434 | 0.82 | FLT1 (0.39) | CYP2C19FLT1FLT4KDRLMNA | |
| SCHEMBL9711575 | 0.78 | NPC1 (0.43) | CYP2C19LMNASMN1; SMN2POLBMAPT | |
| SCHEMBL9711484 | 0.76 | MAPT (0.40) | CYP2C19LMNASMN1; SMN2POLBMAPT | |
| SCHEMBL9711611 | 0.75 | HPD (0.49) | CYP2C19FLT1FLT4KDRLMNA | |
| SCHEMBL9711515 | 0.75 | MAPT (0.41) | CYP2C19LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9711481 | 0.75 | SMN1; SMN2 (0.41) | CYP2C19FLT1FLT4KDRLMNA | |
| SCHEMBL9711475 | 0.75 | TRPV1 (0.42) | CYP2C19FLT1FLT4KDRLMNA | |
| SCHEMBL9229472 | 0.74 | SMN1; SMN2 (0.44) | CYP2C19FLT1FLT4KDRLMNA | |
| SCHEMBL10584278 | 0.72 | ALDH1A1 (0.44) | CYP2C19FLT1FLT4KDRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504056-A | Heterocyclic cyclohexanedione derivative, production thereof, and herbicide | NIPPON SODA CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0641780-A1 | HETEROCYCLIC CYCLOHEXANEDIONE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE | NIPPON SODA CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |