Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.72 |
| ▸ | HPGD | P15428 | 9/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980242 | 0.87 | PDE10A (0.76) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL8980312 | 0.86 | ALDH1A1 (0.72) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL25910919 | 0.84 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL8980346 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL6295964 | 0.81 | ALDH1A1 (0.81) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL22552141 | 0.79 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL29902925 | 0.79 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL29902955 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL22552111 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL22552093 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571822-A | AMINO-2-PHENYL-4-QUINOLONE DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-05 | — | — | US | disclosed |