Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gentisic Acid Ethanolamide SCHEMBL29379843 | 0.83 | NAAA (0.65) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| Gentisic Acid Ethanolamide SCHEMBL1179368 | 0.83 | NAAA (0.65) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL5636971 | 0.81 | ALPL (0.55) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL13545501 | 0.80 | MAPK1 (0.53) | KDM4EALDH1A1CDK1NAAA | |
| SCHEMBL8980687 | 0.80 | CDK1 (0.82) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980647 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980880 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL2158927 | 0.79 | MAPK1 (0.55) | KDM4EALDH1A1CDK1NAAA | |
| SCHEMBL1639721 | 0.79 | P2RX1 (0.54) | KDM4EALDH1A1MAPTP2RX1TMPRSS4 | |
| SCHEMBL13523836 | 0.78 | NAAA (0.56) | KDM4EALDH1A1CDK1NAAASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711286-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004048-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |