Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8981619 | 0.88 | KDM4E (0.57) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL4579120 | 0.86 | KDM4E (0.68) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL8981469 | 0.85 | ALDH1A1 (0.55) | RAB9AALDH1A1KDM4EMAPTCASP1 | |
| SCHEMBL3196899 | 0.85 | RAB9A (0.55) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL13293960 | 0.84 | TAS1R3 (0.63) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL3236742 | 0.84 | ALDH1A1 (0.62) | RAB9ANPC1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL11214981 | 0.83 | APP (0.67) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL15390317 | 0.83 | NPC1 (0.53) | RAB9ANPC1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL4913264 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTCASP1CASP7 | |
| SCHEMBL11324398 | 0.82 | NPC1 (0.72) | RAB9ANPC1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711286-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004048-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |