SCHEMBL8980932

SCHEMBL8980932

CCOC(=O)c1cc2c(=O)c3ccccc3sc2cc1[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
GABRA4 P48169 1/20 0.46
GABRE P78334 1/20 0.46
GABRA6 Q16445 1/20 0.46
GABRG1 Q8N1C3 1/20 0.46
GABRG3 Q99928 1/20 0.46
GABRQ Q9UN88 1/20 0.46
ALDH1A1 P00352 7/20 0.43
LMNA P02545 4/20 0.43
MAPT P10636 4/20 0.43
RAB9A P51151 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29264067 0.81 MAPT (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28634353 0.81 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29278290 0.81 MAPT (0.52) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28728284 0.81 GABRP (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29279645 0.80 GABRP (0.47) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10831569 0.79 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL8956112 0.78 MAPT (0.52) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10421322 0.76 ALDH1A1 (0.55) GABRA1GABRB2ALDH1A1LMNAMAPT
SCHEMBL28628092 0.76 GABRP (0.47) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14044459 0.76 MAPT (0.46) ALDH1A1LMNAMAPTRAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5494944-A BLEND OF MATERIAL POLYMERIZABLE BY FREE RADICAL CATALYSTAND AN IRON COMPOUND CIBA-GEIGY CORPORATION (US) 1996-02-27 US disclosed
US-5371115-A Having sensitizers, electron acceptors selected from peracids, hydroperoxides and quinones; photosensitive, photoresists CIBA-GEIGY CORPORATION (US) 1994-12-06 US disclosed
EP-0295211-B1 Photoresist composition CIBA GEIGY AG (CH) 1994-03-16 EP disclosed
US-5124233-A PHOTORESIST COMPOSITIONS CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
EP-0295211-A2 Photoresist composition CIBA-GEIGY AG (CH) 1988-12-14 EP disclosed
EP-0152377-B1 CURABLE COMPOSITIONS AND THEIR USE CIBA-GEIGY AG (CH) 1987-12-09 EP disclosed
US-4624912-A EXPOSURE TO ELECTRON OR ACTINIC RADIATION, THEN HEATING CIBA-GEIGY CORPORATION (US) 1986-11-25 US disclosed