Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350326 | 0.82 | KDM4E (0.56) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL483616 | 0.82 | KDM4E (0.56) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL8980932 | 0.76 | GABRP (0.46) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL27503798 | 0.75 | MAPT (0.45) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| Ethane SCHEMBL27503799 | 0.74 | CTSV (0.49) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL472542 | 0.74 | KDM4E (0.57) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL8086574 | 0.74 | CTSV (0.51) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL29724161 | 0.74 | KDM4E (0.57) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL5019890 | 0.74 | KDM4E (0.69) | MAPTALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL14491370 | 0.72 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4EL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432368-B2 | Nucleosides with nitro-substituted anthraquin(thi)one, acridin(thi)one, xanthone or xanthione, or thioxanthone or thioxanthione, e.g., 5'-[2-nitro-9-oxo-3-(2-propyloxacarbonyl)thioxanthone]thymidine; used for synthesizing oligonucleotides or nucleic acid chips using light with wavelength above 390 mm | ROCHE NIMBLEGEN, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1589024-B1 | Photolabile protecting groups | NIMBLEGEN SYSTEMS INC (US) | 2007-06-20 | — | — | EP | disclosed |