Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914425 | 0.72 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19273977 | 0.70 | KDM4E (0.67) | KDM4EALDH1A1LMNATDP1HTR1A | |
| SCHEMBL8915296 | 0.70 | KDM4E (0.52) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9535704 | 0.68 | KDM4E (0.59) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8914818 | 0.68 | KDM4E (0.55) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8914989 | 0.67 | KDM4E (0.61) | KDM4EALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL13487187 | 0.65 | MAOA (0.59) | KDM4EALDH1A1HTR1AHTR2AHTR7 | |
| SCHEMBL1193409 | 0.65 | HDAC3 (0.59) | KDM4EALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL30381429 | 0.65 | HDAC3 (0.59) | KDM4EALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL3246920 | 0.65 | MAOA (0.59) | KDM4EALDH1A1HTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |