Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CD44 | P16070 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914425 | 0.89 | ALDH1A1 (0.52) | KDM4EALDH1A1TDP1LMNACD44 | |
| SCHEMBL8914311 | 0.80 | ALOX15 (0.39) | KDM4EALDH1A1DRD2DRD3POLB | |
| SCHEMBL8914916 | 0.79 | RAB9A (0.49) | KDM4EALDH1A1DRD2DRD3HTR1A | |
| SCHEMBL8918377 | 0.79 | SIGMAR1 (0.42) | KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL7008816 | 0.79 | HTR1A (0.46) | KDM4EALDH1A1TDP1LMNACD44 | |
| SCHEMBL8914889 | 0.78 | GRIN2B (0.47) | KDM4EALDH1A1LMNADRD2DRD3 | |
| SCHEMBL8914888 | 0.78 | DRD2 (0.42) | KDM4EALDH1A1TDP1LMNACD44 | |
| SCHEMBL8915109 | 0.76 | RAB9A (0.43) | KDM4EALDH1A1LMNADRD2DRD3 | |
| SCHEMBL8915115 | 0.76 | RAB9A (0.40) | KDM4EALDH1A1TDP1LMNACD44 | |
| SCHEMBL8915967 | 0.75 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |