Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157722 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4EPOLBTSHRTACR1 | |
| SCHEMBL8743578 | 0.74 | TSHR (0.54) | ALDH1A1KDM4EPOLBTSHRTACR1 | |
| SCHEMBL5349731 | 0.73 | TSHR (0.52) | ALDH1A1KDM4EPOLBTSHRTACR1 | |
| SCHEMBL23227891 | 0.73 | TSHR (0.52) | ALDH1A1KDM4EPOLBTSHRTACR1 | |
| SCHEMBL4860052 | 0.73 | TSHR (0.52) | ALDH1A1KDM4EPOLBTSHRTACR1 | |
| SCHEMBL18640775 | 0.72 | TSHR (0.56) | ALDH1A1KDM4EPOLBTSHRTACR1 | |
| Propane SCHEMBL11584021 | 0.71 | TSHR (0.83) | ALDH1A1KDM4EPOLBTSHRTACR1 | |
| SCHEMBL9544613 | 0.70 | KDM4E (0.50) | ALDH1A1KDM4EPOLBTSHRTACR1 | |
| SCHEMBL8983816 | 0.70 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1CYP3A4CYP2C19 | |
| SCHEMBL476765 | 0.69 | KDM4E (0.53) | ALDH1A1KDM4EPOLBTSHRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504902-B1 | Phosphoric acid ester derivatives, process for preparing the derivative and insecticidal and miticidal composition comprising the derivative | OTSUKA KAGAKU KK (JP) | 1996-06-05 | — | — | EP | disclosed |
| EP-0504902-A1 | Phosphoric acid ester derivatives, process for preparing the derivative and insecticidal and miticidal composition comprising the derivative | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-09-23 | — | — | EP | disclosed |