Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.60 |
| ▸ | FEN1 | P39748 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515732 | 0.87 | ERCC5 (0.59) | ERCC5FEN1MAPTL3MBTL1SMO | |
| SCHEMBL9061917 | 0.84 | PIK3CA (0.53) | ERCC5FEN1TSHRMAPTL3MBTL1 | |
| SCHEMBL3282076 | 0.83 | MAPT (0.49) | ERCC5FEN1TSHRMAPTL3MBTL1 | |
| SCHEMBL257528 | 0.83 | SMN1; SMN2 (0.49) | ERCC5FEN1TSHRMAPTL3MBTL1 | |
| SCHEMBL3279897 | 0.83 | HTT (0.49) | ERCC5FEN1TSHRMAPTL3MBTL1 | |
| SCHEMBL4748426 | 0.81 | USP2 (0.62) | ERCC5FEN1TSHRHTTALDH1A1 | |
| SCHEMBL2473843 | 0.81 | NAPRT (0.53) | ERCC5FEN1TSHRGAAMEN1 | |
| SCHEMBL7129795 | 0.80 | MEN1 (0.62) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11503697 | 0.79 | CTSS (0.46) | MAPTL3MBTL1GAACES1P2RX7 | |
| SCHEMBL10658504 | 0.77 | PIK3CA (0.54) | MAPTL3MBTL1HTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0611366-A1 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| WO-1993009074-A2 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |