Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291203 | 0.90 | MCL1 (0.47) | MCL1MAPK1KDM4EKMT2ANPC1 | |
| SCHEMBL7762851 | 0.83 | NAAA (0.45) | MCL1MAPK1NAAATLR4 | |
| SCHEMBL7757533 | 0.83 | NAAA (0.45) | MCL1MAPK1NAAATLR4 | |
| SCHEMBL9665167 | 0.83 | NAAA (0.45) | MCL1MAPK1NAAATLR4 | |
| SCHEMBL29191656 | 0.81 | NAAA (0.42) | MCL1MAPK1NPC1RAB9ANAAA | |
| SCHEMBL28362680 | 0.80 | MCL1 (0.40) | MCL1MAPK1KDM4EKMT2ANPC1 | |
| SCHEMBL535448 | 0.79 | LMNA (0.45) | MCL1MAPK1KMT2ANPC1RAB9A | |
| SCHEMBL7095347 | 0.79 | LMNA (0.40) | MCL1MAPK1KMT2ANAAAALDH1A1 | |
| SCHEMBL17849965 | 0.77 | MCL1 (0.40) | MCL1MAPK1KDM4EKMT2ANPC1 | |
| SCHEMBL10339687 | 0.77 | MCL1 (0.49) | MCL1MAPK1KDM4EKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711746-A1 | Process for preparing hydroxycarboxylic acids | UNILEVER PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| US-5502226-A | SELECTIVE REDUCTION OF DIKETONE TO KETO ACIDS USING HYDROGEN IN THE PRESENCE OF BASE | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1996-03-26 | — | — | US | disclosed |