SCHEMBL238218

SCHEMBL238218

[SiH3]OC(Cc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
SLC6A2 P23975 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
KIF11 P52732 3/20 0.39
KCNA5 P22460 1/20 0.38
LMNA P02545 1/20 0.38
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 1/20 0.36
TSHR P16473 1/20 0.36
FDPS P14324 1/20 0.35
CALM1 P0DP23 1/20 0.35
CYP3A4 P08684 2/20 0.34
RECQL P46063 1/20 0.34
TRPA1 O75762 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482019 0.87 KIF11 (0.42) CYP1A2CYP2C9CYP2C19KIF11LMNA
SCHEMBL7001871 0.82 CYP1A2 (0.52) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL9614595 0.78 CYP1A2 (0.54) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL11248544 0.78 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL765190 0.78 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL5145585 0.78 CYP1A2 (0.48) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL4454996 0.77 CYP1A2 (0.47) CYP1A2CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL1262885 0.76 TSHR (0.39) CYP1A2CYP2C9CYP2C19TAAR1KIF11
SCHEMBL4079192 0.76 MAPK1 (0.34) CYP1A2CYP2C9CYP2C19TAAR1KIF11
SCHEMBL22551444 0.76 MAPK1 (0.34) CYP1A2CYP2C9CYP2C19TAAR1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1084 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240309144-A1 SILANE MODIFIED ALIPHATIC POLYUREA EVONIK OPERATIONS GMBH (DE) 2024-09-19 US claimed
EP-4370573-A1 SILANE MODIFIED ALIPHATIC POLYUREA Evonik Operations GmbH (DE) 2024-05-22 EP claimed
CN-117203256-A Silane-modified aliphatic polyureas 赢创运营有限公司 2023-12-08 CN claimed
CN-116943660-A Organic modified Fischer-Tropsch synthesis iron-based catalyst and application thereof 国家能源投资集团有限责任公司 2023-10-27 CN claimed
CN-116920892-A High-stability iron-based catalyst for Fischer-Tropsch synthesis and application thereof 国家能源投资集团有限责任公司 2023-10-24 CN claimed
CN-115155113-B Structure for organic silicon defoamer and synthesis method thereof 佛山市南海大田化学有限公司 2023-09-29 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
CN-115105868-B Organic silicon defoamer and preparation method thereof 佛山市南海大田化学有限公司 2023-07-18 CN claimed
CN-116082843-A Heat-resistant addition type silicone rubber composition and preparation method thereof 东莞市贝特利新材料有限公司 2023-05-09 CN claimed
CN-114456385-B Preparation method of MDT type methylphenyl silicone oil for cosmetics 湖南科技学院 2023-04-21 CN claimed
US-20030069372-A1 Olefin polymerization catalyst and process for preparing polyolefins with said catalyst FORMOSA PLASTICS CORPORATION, U.S.A. 2003-04-10 US claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
US-6444727-B1 SURFACE TREATMENT WITH ORGANOSILICON COMPOUNDS BRIDGESTONE CORPORATION (JP) 2002-09-03 US claimed
EP-1088854-A2 Modified carbon black, process for producing the modified carbon black, rubber composition and pneumatic tire BRIDGESTONE CORPORATION (JP) 2001-04-04 EP claimed
EP-0618931-B2 A MODIFIED MONOCYCLOPENTADIENYL TRANSITION METAL/ALUMOXANE CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINS EXXON CHEMICAL PATENTS INC (US) 2000-11-02 EP claimed
US-6017995-A AN AQUEOUS SUSPENSION COMPRISING MICA, AT LEAST ONE SILANE, A POLYSILOXANE, A COMPOUND CATALYZING THE HYDROLYSIS AND/OR COUPLING REACTION AND ADDITIVES; IMPROVING THE FORMED SHEET MECHANICAL AND ELECTRICAL PROPERTIES WACKER-CHEMIE GMBH (DE) 2000-01-25 US claimed
US-5980683-A Production of a support element module for embedding into smart cards or other data carrier cards INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-11-09 US claimed
EP-0457175-B1 Method of purification of alkoxysilanes TOSHIBA SILICONE (JP) 1997-02-12 EP claimed
US-5547675-A HIGH MOLECULAR WEIGHT POLYMERS EXXON CHEMICAL PATENTS INC. (US) 1996-08-20 US claimed
EP-0457175-A2 Method of purification of alkoxysilanes TOSHIBA SILICONE CO., LTD. (JP) 1991-11-21 EP claimed