Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.76 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655257 | 0.87 | MGLL (0.66) | MGLLENPP2POLBRAB9ANPC1 | |
| SCHEMBL9459601 | 0.87 | MGLL (0.66) | MGLLENPP2POLBRAB9ANPC1 | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.87 | POLB (0.78) | MGLLENPP2POLBRAB9ANPC1 | |
| SCHEMBL27498433 | 0.86 | MGLL (0.74) | MGLLENPP2POLBRAB9ANPC1 | |
| SCHEMBL907590 | 0.85 | ENPP2 (0.85) | MGLLENPP2POLBRAB9ANPC1 | |
| SCHEMBL17927947 | 0.85 | MGLL (0.72) | MGLLENPP2POLBRAB9ANPC1 | |
| SCHEMBL5853166 | 0.85 | MGLL (0.72) | MGLLENPP2POLBRAB9ANPC1 | |
| SCHEMBL15648038 | 0.85 | MGLL (0.72) | MGLLENPP2POLBRAB9ANPC1 | |
| SCHEMBL2571440 | 0.85 | MGLL (0.72) | MGLLENPP2POLBRAB9ANPC1 | |
| SCHEMBL1034658 | 0.85 | MGLL (0.74) | MGLLENPP2POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482947-A | ENZYME INHIBITORS FOR HIV PROTEASE INHIBITION FROM UREA OR THIOUREA COMPOUNDS | TALLEY JOHN J (US) | 1996-01-09 | — | — | US | disclosed |
| CN-1091432-A | Can suppress the active peptide of hiv protease, its preparation with and medical use | SANKYO CO (JP) | 1994-08-31 | — | — | CN | disclosed |