Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985043 | 1.00 | MMP1 (0.51) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL3439467 | 0.90 | NR1H4 (0.49) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL31389315 | 0.90 | NR1H4 (0.49) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL1164581 | 0.90 | NR1H4 (0.49) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL2174596 | 0.87 | TTR (0.47) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL2174598 | 0.87 | TTR (0.47) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL5598396 | 0.85 | L3MBTL1 (0.48) | MMP1MMP2MMP9AKR1C3CA12 | |
| SCHEMBL29952891 | 0.85 | GLS (0.52) | GLSBRD4KDM4ACA12CA1 | |
| SCHEMBL5598393 | 0.85 | L3MBTL1 (0.48) | MMP1MMP2MMP9AKR1C3CA12 | |
| SCHEMBL209838 | 0.85 | GLS (0.52) | GLSBRD4KDM4ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541286-A | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids | SCIOS NOVA INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5444048-A | Antiinflammatory agents, analgesics | SCIOS NOVA, INC. (US) | 1995-08-22 | — | — | US | disclosed |