SCHEMBL8985167

SCHEMBL8985167

Cc1ccc(OC#N)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
ACHE P22303 1/20 0.41
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 1/20 0.38
L3MBTL1 Q9Y468 5/20 0.37
KMT2A Q03164 3/20 0.37
NPC1 O15118 1/20 0.37
NFKB1 P19838 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
MAPT P10636 1/20 0.36
HTR1A P08908 2/20 0.36
MEN1 O00255 2/20 0.35
HPGD P15428 2/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489134 1.00 GAA (0.44) GAAACHETP53TDP1SMN1; SMN2
SCHEMBL11033634 0.83 ALDH1A1 (0.38) GAATDP1ALDH1A1CYP3A4KMT2A
SCHEMBL11108932 0.83 TSHR (0.44) GAAACHETDP1SMN1; SMN2ALDH1A1
SCHEMBL11338994 0.81 AR (0.34) GAAMAPTARCA1CA2
SCHEMBL9419423 0.79 ALDH1A1 (0.39) TP53TDP1SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL3419472 0.79 AR (0.41) SMN1; SMN2L3MBTL1KMT2AMAPTMEN1
SCHEMBL21439789 0.79 ACHE (0.43) GAAACHETP53TDP1SMN1; SMN2
SCHEMBL9348336 0.79 TSHR (0.45) GAATP53SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL9419412 0.79 CYP1A2 (0.45) GAAACHETDP1SMN1; SMN2ALDH1A1
SCHEMBL16707442 0.79 TAAR1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101910308-B Curing composition and cured product prepared by using the same LG CHEMICAL LTD 2012-11-21 CN claimed
CN-101910308-A Curing composition and cured product prepared by using the same LG CHEMICAL LTD 2010-12-08 CN claimed
CN-118251445-A Cyclic organosiloxane containing imide bond and polymerizable unsaturated bond and curable resin composition containing the same 信越化学工业株式会社 2024-06-25 CN disclosed
CN-118043384-A Prepreg, laminate and printed circuit board 三菱瓦斯化学株式会社 2024-05-14 CN disclosed
CN-112236464-B Resin composition, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2024-02-23 CN disclosed
CN-117529509-A Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2024-02-06 CN disclosed
CN-117500851-A Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2024-02-02 CN disclosed
CN-117500850-A Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2024-02-02 CN disclosed
CN-117355545-A Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2024-01-05 CN disclosed
CN-117222682-A Cured resin composition and cured product thereof 日本化药株式会社 2023-12-12 CN disclosed
CN-116940617-A Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 日本化药株式会社 2023-10-24 CN disclosed
CN-1726259-A Thermoplastic polyimide resin film, multilayer body and method for manufacturing printed wiring board composed of same KANEGAFUCHI CHEMICAL IND (JP) 2006-01-25 CN disclosed
CN-1464898-A Resin composition KANEGAFUCHI CHEMICAL IND (JP) 2003-12-31 CN disclosed
CN-1379800-A Cyanate ester based thermoset compositions GEN ELECTRIC (US) 2002-11-13 CN disclosed
CN-1229817-A Cyanate ester based thermoset compositions GEN ELECTRIC (US) 1999-09-29 CN disclosed
EP-0476589-B1 Multi-layer wiring substrate and production thereof HITACHI LTD (JP) 1996-06-12 EP disclosed
EP-0271833-B1 Process for the preparation of aminopyrimidines HOECHST SCHERING AGREVO GMBH (DE) 1994-09-07 EP disclosed
EP-0476589-A2 Multi-layer wiring substrate and production thereof HITACHI, LTD. (JP) 1992-03-25 EP disclosed
US-4831138-A FROM PROPANEDIIMIDATES DERIVATIVES AND CYANURATES HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-16 US disclosed
EP-0271833-A2 Process for the preparation of aminopyrimidines Hoechst Schering AgrEvo GmbH (DE) 1988-06-22 EP disclosed