SCHEMBL8985182

SCHEMBL8985182

N#CNc1cccc(NC#N)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.42
▸ MAPT P10636 5/20 0.42
▸ MEN1 O00255 5/20 0.42
▸ KMT2A Q03164 5/20 0.42
▸ AR P10275 1/20 0.42
▸ GPR35 Q9HC97 1/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ CISD1 Q9NZ45 1/20 0.34
▸ IDO1 P14902 1/20 0.33
▸ KCNA5 P22460 1/20 0.32
▸ KCNK3 O14649 1/20 0.32
▸ KCNK9 Q9NPC2 1/20 0.32
▸ JAK2 O60674 2/20 0.32
▸ JAK1 P23458 1/20 0.32
▸ KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14128157 0.84 CYP3A4 (0.52) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL2295342 0.84 KMT2A (0.53) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL6586488 0.84 SIGMAR1 (0.40) IDO1
SCHEMBL9492682 0.84 MAPT (0.53) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL12123166 0.84 MAPT (0.52) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL11506421 0.82 JAK2 (0.38) MEN1KMT2AJAK2JAK1LMNA
SCHEMBL1259441 0.80 — —
Water SCHEMBL11606809 0.80 ALDH1A1 (0.45) ALDH1A1MAPTMEN1KMT2AAR
Water SCHEMBL11606806 0.80 ALDH1A1 (0.45) ALDH1A1MAPTMEN1KMT2AAR
Benzene SCHEMBL28295973 0.80 ALDH1A1 (0.45) ALDH1A1MAPTMEN1KMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 — — EP claimed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 — — US claimed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 — — EP claimed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 — — US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 — — US claimed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 — — US claimed
JP-61004778-A — — None — — JP disclosed
JP-59196363-A — — None — — JP disclosed
JP-60163929-A — — None — — JP disclosed
CN-111107975-A Resin composition, method for producing three-dimensional object using same, three-dimensional object, fitting for holding object, and industrial robot using same 柯尼卡美能达株式会社 2020-05-05 — — CN disclosed
EP-0476589-B1 Multi-layer wiring substrate and production thereof HITACHI LTD (JP) 1996-06-12 — — EP disclosed
EP-0476589-A2 Multi-layer wiring substrate and production thereof HITACHI, LTD. (JP) 1992-03-25 — — EP disclosed
EP-0153603-B1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT, AND PRODUCTION OF CURED PRODUCT HITACHI, LTD. (JP) 1992-01-02 — — EP disclosed
EP-0078039-A1 Thermosetting resin composition, prepolymer thereof and cured article thereof Hitachi, Ltd. (JP) 1983-05-04 — — EP disclosed
US-4150051-A N-Cyanosulfonamide compounds CIBA-GEIGY CORPORATION (US) 1979-04-17 — — US disclosed
US-4080483-A COATINGS, MOLDING MATERIALS, LAMINATION CIBA-GEIGY CORPORATION (US) 1978-03-21 — — US disclosed
US-4075185-A ADDITION POLYMERIZATION CIBA-GEIGY CORPORATION (US) 1978-02-21 — — US disclosed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 — — US disclosed
US-4049711-A POLYSULFONAMIDE MONOMERS CIBA-GEIGY CORPORATION (US) 1977-09-20 — — US disclosed
US-3944526-A N-cyanosulfonamide resins and intermediates therefor and products thereof CIBA-GEIGY CORPORATION (US) 1976-03-16 — — US disclosed
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