SCHEMBL8985182

SCHEMBL8985182

N#CNc1cccc(NC#N)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
MAPT P10636 5/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
AR P10275 1/20 0.42
GPR35 Q9HC97 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HSD17B10 Q99714 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
CISD1 Q9NZ45 1/20 0.34
IDO1 P14902 1/20 0.33
KCNA5 P22460 1/20 0.32
KCNK3 O14649 1/20 0.32
KCNK9 Q9NPC2 1/20 0.32
JAK2 O60674 2/20 0.32
JAK1 P23458 1/20 0.32
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2295342 0.84 KMT2A (0.53) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL9492682 0.84 MAPT (0.53) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL6586488 0.84 SIGMAR1 (0.40) IDO1
SCHEMBL14128157 0.84 CYP3A4 (0.52) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL12123166 0.84 MAPT (0.52) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL11506421 0.82 JAK2 (0.38) MEN1KMT2AJAK2JAK1LMNA
Water SCHEMBL11606806 0.80 ALDH1A1 (0.45) ALDH1A1MAPTMEN1KMT2AAR
Water SCHEMBL11606809 0.80 ALDH1A1 (0.45) ALDH1A1MAPTMEN1KMT2AAR
Benzene SCHEMBL28295973 0.80 ALDH1A1 (0.45) ALDH1A1MAPTMEN1KMT2AAR
SCHEMBL1259441 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP claimed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US claimed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP claimed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US claimed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US claimed
JP-61004778-A None JP disclosed
JP-59196363-A None JP disclosed
JP-60163929-A None JP disclosed
CN-111107975-A Resin composition, method for producing three-dimensional object using same, three-dimensional object, fitting for holding object, and industrial robot using same 柯尼卡美能达株式会社 2020-05-05 CN disclosed
EP-0476589-B1 Multi-layer wiring substrate and production thereof HITACHI LTD (JP) 1996-06-12 EP disclosed
EP-0476589-A2 Multi-layer wiring substrate and production thereof HITACHI, LTD. (JP) 1992-03-25 EP disclosed
EP-0153603-B1 THERMOSETTING RESIN COMPOSITION, CURED PRODUCT, AND PRODUCTION OF CURED PRODUCT HITACHI, LTD. (JP) 1992-01-02 EP disclosed
EP-0078039-A1 Thermosetting resin composition, prepolymer thereof and cured article thereof Hitachi, Ltd. (JP) 1983-05-04 EP disclosed
US-4150051-A N-Cyanosulfonamide compounds CIBA-GEIGY CORPORATION (US) 1979-04-17 US disclosed
US-4080483-A COATINGS, MOLDING MATERIALS, LAMINATION CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4075185-A ADDITION POLYMERIZATION CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed
US-4049711-A POLYSULFONAMIDE MONOMERS CIBA-GEIGY CORPORATION (US) 1977-09-20 US disclosed
US-3944526-A N-cyanosulfonamide resins and intermediates therefor and products thereof CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed