Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.45 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985206 | 0.93 | MAPK14 (0.54) | MAPK14KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8985425 | 0.91 | MAPK14 (0.52) | MAPK14KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8985326 | 0.91 | MAPK14 (0.52) | MAPK14KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8985276 | 0.91 | OPRD1 (0.66) | MAPK14KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8985386 | 0.90 | PTGS2 (0.63) | MAPK14KDM4EHPGDPTGS2PTGS1 | |
| SCHEMBL8985447 | 0.89 | MAPK14 (0.50) | MAPK14KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8985415 | 0.89 | PTGS2 (0.50) | MAPK14KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8985371 | 0.88 | PTGS2 (0.57) | MAPK14KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8985269 | 0.88 | MAPK14 (0.49) | MAPK14KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8985285 | 0.88 | PTGS2 (0.52) | MAPK14KDM4EHPGDNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |