Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985511 | 0.94 | OPRD1 (0.74) | OPRD1PTGS1PTGS2EP300KDM4E | |
| SCHEMBL8985191 | 0.91 | MAPK14 (0.60) | OPRD1PTGS1PTGS2KDM4EHPGD | |
| SCHEMBL8985362 | 0.86 | OPRD1 (0.71) | OPRD1PTGS1PTGS2EP300KDM4E | |
| SCHEMBL8985383 | 0.86 | MAPK14 (0.70) | OPRD1PTGS1PTGS2EP300KDM4E | |
| SCHEMBL8985238 | 0.85 | OPRD1 (0.63) | OPRD1PTGS1PTGS2EP300KDM4E | |
| SCHEMBL8985206 | 0.85 | MAPK14 (0.54) | OPRD1PTGS1PTGS2KDM4EHPGD | |
| SCHEMBL8985361 | 0.84 | OPRD1 (0.62) | OPRD1PTGS1PTGS2EP300KDM4E | |
| SCHEMBL8985326 | 0.82 | MAPK14 (0.52) | OPRD1PTGS1PTGS2KDM4EHPGD | |
| SCHEMBL8985425 | 0.82 | MAPK14 (0.52) | OPRD1PTGS1PTGS2KDM4EHPGD | |
| SCHEMBL8985484 | 0.82 | OPRD1 (0.62) | OPRD1PTGS1PTGS2EP300HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |