Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872876 | 0.83 | PKM (0.62) | NPC1RAB9ASMN1; SMN2MAPK1GSK3B | |
| SCHEMBL8985359 | 0.80 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GSK3BMAPT | |
| SCHEMBL668743 | 0.80 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2GSK3BMAPT | |
| SCHEMBL7832348 | 0.80 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2MAPK1GSK3B | |
| SCHEMBL6386624 | 0.80 | SRD5A2 (0.57) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4319309 | 0.80 | CES2 (0.61) | NPC1RAB9AMAPK1GSK3BMAPT | |
| SCHEMBL199347 | 0.80 | CRHBP (0.62) | KDM4ENPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL13236074 | 0.79 | MAPT (0.53) | RAB9AMAPK1GSK3BMAPTPKM | |
| SCHEMBL28872884 | 0.79 | MEN1 (0.53) | KDM4ENPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL10477098 | 0.79 | GSK3B (0.51) | MAPK1GSK3BMAPTPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |