Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512539 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8985381 | 0.81 | PTGS1 (0.60) | PTGS2PTGS1 | |
| SCHEMBL9259229 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8985356 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8985476 | 0.80 | PTGS1 (0.62) | PTGS2PTGS1 | |
| SCHEMBL6513427 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL515001 | 0.78 | CA1 (0.61) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL8985340 | 0.77 | PTGS2 (0.70) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL6513901 | 0.75 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6517779 | 0.74 | PTGS2 (0.68) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |