Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 11/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.58 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843937 | 0.83 | MAPK14 (0.79) | PTGS1PTGS2MAPK14 | |
| SCHEMBL8985240 | 0.81 | PTGS2 (0.69) | PTGS1PTGS2 | |
| SCHEMBL8985476 | 0.81 | PTGS1 (0.62) | PTGS1PTGS2 | |
| SCHEMBL2961612 | 0.77 | HSPB1 (0.67) | PTGS1MAPK14HSPB1GCGRPOLB | |
| SCHEMBL27458731 | 0.77 | PTGS1 (0.46) | PTGS1PTGS2MAPK14HSPB1POLB | |
| Water SCHEMBL4218173 | 0.75 | HSPB1 (0.64) | PTGS1MAPK14HSPB1GCGRPOLB | |
| SCHEMBL536 | 0.75 | HSPB1 (0.75) | HSPB1POLB | |
| SCHEMBL7026994 | 0.75 | HSPB1 (0.75) | HSPB1POLB | |
| SCHEMBL7788130 | 0.75 | PTGS2 (0.73) | PTGS1PTGS2MAPK14 | |
| SCHEMBL9259229 | 0.75 | PTGS2 (1.00) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |