Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 11/20 | 0.70 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567384 | 0.83 | PTGS1 (1.00) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985431 | 0.83 | PTGS1 (1.00) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985534 | 0.80 | PTGS1 (0.71) | PTGS1MAPK14PTGS2 | |
| SCHEMBL6517923 | 0.74 | PTGS1 (0.68) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985537 | 0.72 | MAPK14 (0.51) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985370 | 0.72 | MAPK14 (0.53) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985394 | 0.72 | PTGS1 (0.37) | PTGS1MAPK14PTGS2 | |
| SCHEMBL8985476 | 0.71 | PTGS1 (0.62) | PTGS1PTGS2 | |
| SCHEMBL8985416 | 0.70 | NPC1 (0.40) | PTGS1MAPK14PTGS2 | |
| SCHEMBL6725855 | 0.70 | PTGS1 (0.57) | PTGS1MAPK14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |