Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | EP300 | Q09472 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985341 | 0.88 | EP300 (0.41) | PTGS1SLC6A4SLC6A2SLC6A3EP300 | |
| SCHEMBL8985538 | 0.87 | PTGS1 (0.51) | PTGS1SLC6A4SLC6A2SLC6A3EP300 | |
| Hydrochloric Acid SCHEMBL8985440 | 0.86 | PTGS1 (0.50) | PTGS1SLC6A4SLC6A2SLC6A3EP300 | |
| SCHEMBL8985236 | 0.85 | SLC6A4 (0.43) | PTGS1SLC6A4SLC6A2SLC6A3EP300 | |
| SCHEMBL8985480 | 0.83 | SLC6A4 (0.43) | PTGS1SLC6A4SLC6A2SLC6A3EP300 | |
| SCHEMBL8985455 | 0.80 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3EP300PTGS2 | |
| Hydrochloric Acid SCHEMBL8985508 | 0.80 | PTGS2 (0.53) | PTGS1PTGS2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8985223 | 0.77 | PTGS2 (0.50) | PTGS1EP300PTGS2MAPK14CYP1A2 | |
| SCHEMBL8985346 | 0.77 | PTGS1 (0.48) | PTGS1SLC6A4SLC6A2SLC6A3EP300 | |
| SCHEMBL8985416 | 0.76 | NPC1 (0.40) | PTGS1PTGS2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |