Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985279 | 0.84 | MAPK14 (0.53) | MAPK14MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8985313 | 0.84 | MAPK14 (0.58) | MAPK14MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8985532 | 0.84 | MAPK14 (0.53) | MAPK14MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8985530 | 0.83 | MAPK14 (0.52) | MAPK14MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8985473 | 0.83 | MAPK14 (0.56) | MAPK14MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8985272 | 0.83 | MAPK14 (0.52) | MAPK14MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8985524 | 0.82 | MAPK14 (0.51) | MAPK14MAPTNPC1ALDH1A1GAA | |
| SCHEMBL8985412 | 0.80 | MAPK14 (0.59) | MAPK14MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL6018669 | 0.79 | MAPK14 (0.65) | MAPK14MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL8985541 | 0.76 | MAPK14 (0.56) | MAPK14NPC1ALDH1A1LMNAOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |