Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985419 | 0.86 | MAPK14 (0.52) | MAPK14OPRD1PTGS2PTGS1NPC1 | |
| SCHEMBL8985533 | 0.84 | OPRD1 (0.64) | MAPK14OPRD1PTGS2PTGS1NPC1 | |
| SCHEMBL8985250 | 0.83 | MAPK14 (0.73) | MAPK14OPRD1PTGS2PTGS1ALDH1A1 | |
| SCHEMBL8985268 | 0.83 | MAPK14 (0.57) | MAPK14OPRD1PTGS2PTGS1NPC1 | |
| SCHEMBL8985312 | 0.82 | MAPK14 (0.48) | MAPK14OPRD1PTGS2PTGS1NPC1 | |
| SCHEMBL8985370 | 0.82 | MAPK14 (0.53) | MAPK14OPRD1PTGS2PTGS1NPC1 | |
| SCHEMBL8985541 | 0.81 | MAPK14 (0.56) | MAPK14OPRD1PTGS2PTGS1NPC1 | |
| SCHEMBL8985226 | 0.81 | MAPK14 (0.47) | MAPK14OPRD1PTGS2PTGS1NPC1 | |
| SCHEMBL8985239 | 0.81 | NPC1 (0.50) | MAPK14OPRD1PTGS2PTGS1NPC1 | |
| SCHEMBL8985338 | 0.80 | MAPK14 (0.46) | MAPK14OPRD1PTGS2PTGS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |