Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP10 | Q14694 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985275 | 0.85 | MAPK14 (0.53) | MAPK14PRKCZRAB9AGAAMAPT | |
| SCHEMBL8985268 | 0.84 | MAPK14 (0.57) | MAPK14PRKCZRAB9AGAAMAPT | |
| SCHEMBL8985432 | 0.84 | MAPK14 (0.46) | MAPK14RAB9AOPRD1KDM4ETDP1 | |
| SCHEMBL8985312 | 0.84 | MAPK14 (0.48) | MAPK14RAB9AMAPTOPRD1ALDH1A1 | |
| SCHEMBL8985313 | 0.81 | MAPK14 (0.58) | MAPK14PRKCZRAB9AMAPTOPRD1 | |
| SCHEMBL8985524 | 0.81 | MAPK14 (0.51) | MAPK14PRKCZGAAMAPTOPRD1 | |
| SCHEMBL8985532 | 0.80 | MAPK14 (0.53) | MAPK14PRKCZRAB9AMAPTOPRD1 | |
| SCHEMBL8985530 | 0.79 | MAPK14 (0.52) | MAPK14PRKCZRAB9AGAAMAPT | |
| SCHEMBL8985412 | 0.77 | MAPK14 (0.59) | MAPK14PRKCZRAB9AGAAMAPT | |
| SCHEMBL8985460 | 0.76 | PTGS2 (0.46) | RAB9AMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |