Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.49 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | USP10 | Q14694 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985473 | 0.86 | MAPK14 (0.56) | MAPK14PRKCZPTGS2PTGS1GAA | |
| SCHEMBL8985279 | 0.85 | MAPK14 (0.53) | MAPK14PRKCZARGAARAB9A | |
| SCHEMBL8985205 | 0.84 | PTGS2 (0.55) | MAPK14PTGS2PTGS1RAB9AOPRD1 | |
| SCHEMBL8985434 | 0.81 | MAPK14 (0.52) | MAPK14PTGS2ARPTGS1GAA | |
| SCHEMBL8985406 | 0.81 | MAPK14 (0.51) | MAPK14PTGS2PTGS1GAAOPRD1 | |
| SCHEMBL8985407 | 0.81 | MAPK14 (0.51) | MAPK14PRKCZPTGS2PTGS1GAA | |
| SCHEMBL8985340 | 0.76 | PTGS2 (0.70) | PTGS2PTGS1CA9 | |
| SCHEMBL6018669 | 0.75 | MAPK14 (0.65) | MAPK14GAARAB9AMAPTOPRD1 | |
| SCHEMBL7617599 | 0.74 | PTGS2 (0.64) | PTGS2PTGS1GAARAB9AMAPT | |
| SCHEMBL28446734 | 0.73 | MEN1 (0.51) | PRKCZPTGS2ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |