Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 10/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985293 | 0.79 | MC4R (0.37) | MC4RIKBKBCHUKPTGS2 | |
| SCHEMBL8985469 | 0.76 | AURKA (0.47) | TGM2IKBKBCHUKPTGS2 | |
| SCHEMBL8985260 | 0.69 | PTGS2 (0.65) | PTGS2 | |
| SCHEMBL9203678 | 0.67 | EPHX2 (0.48) | PTGS2 | |
| SCHEMBL8985406 | 0.67 | MAPK14 (0.51) | GHSRPTGS2 | |
| SCHEMBL8985189 | 0.67 | PTGS2 (0.49) | PTGS2 | |
| SCHEMBL14624916 | 0.64 | CA12 (0.49) | TGM2 | |
| SCHEMBL7759448 | 0.62 | TGM2 (0.61) | TGM2PTGS2 | |
| SCHEMBL12463872 | 0.62 | CA1 (0.70) | — | |
| SCHEMBL9206865 | 0.62 | EPHX2 (0.52) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |