Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246285 | 0.88 | PTGS2 (0.51) | PTGS2PTGS1MAPK14KDM4EMT-CO1 | |
| SCHEMBL8985490 | 0.87 | PTGS2 (0.67) | PTGS2PTGS1MAPK14KDM4EMT-CO1 | |
| SCHEMBL8985205 | 0.84 | PTGS2 (0.55) | PTGS2PTGS1MAPK14KDM4EMT-CO1 | |
| SCHEMBL8985473 | 0.83 | MAPK14 (0.56) | PTGS2PTGS1MAPK14KDM4EMT-CO1 | |
| SCHEMBL8985408 | 0.81 | PTGS2 (0.52) | PTGS2PTGS1MAPK14KDM4EMT-CO1 | |
| SCHEMBL8985314 | 0.80 | PTGS2 (0.75) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985337 | 0.78 | PTGS2 (0.52) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL8985461 | 0.78 | PTGS2 (0.68) | PTGS2PTGS1MAPK14KDM4EMT-CO1 | |
| SCHEMBL7617599 | 0.77 | PTGS2 (0.64) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL7620139 | 0.76 | PTGS2 (0.78) | PTGS2PTGS1MAPK14KDM4EMT-CO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |